Gene name:
Tnfsf11 (Opgl;Rankl;Trance) ;
Protein name:
Tumor necrosis factor ligand superfamily member 11 ;
Alternative:
Osteoprotegerin ligand (OPGL) ;Osteoclast differentiation factor (ODF) ;TNF-related activation-induced cytokine (TRANCE) ;Receptor activator of nuclear factor kappa-B ligand (RANKL) ;
CD:
CD254 ;
Organism:
Rat (Rattus norvegicus).
General Annotation
Function:
Cytokine that binds to TNFRSF11B/OPG and to TNFRSF11A/RANK. Osteoclast differentiation and activation factor. Augments the ability of dendritic cells to stimulate naive T-cell proliferation. May be an important regulator of interactions between T-cells and dendritic cells and may play a role in the regulation of the T-cell-dependent immune response. May also play an important role in enhanced bone-resorption in humoral hypercalcemia of malignancy.
Subcellular Location:
Tumor necrosis factor ligand superfamily member 11, soluble form
Secreted
Protein Attributes:
50:
MRRANRDYGK | YLRGSEEMGS | CPGVPHEGPL | HPAPSAPAPA | PPPAASRFMF |
100:
LALLGLGLGQ | VVCSIALFLY | FRAQMDPNRI | SEDSTRCFYR | ILRLRENTGL |
150:
QDSTLESEDT | EALPDSCRRM | KQAFQGAVQR | ELQHIVGPQR | FSGVPAMMEG |
200:
SWLDVARRGK | PEAQPFAHLT | INAADIPSGS | HKVSLSSWYH | DRGWAKISNM |
250:
TLSNGKLRVN | QDGFYYLYAN | ICFRHHETSG | SVPADYLQLM | VYVVKTSIKI |
300:
PSSHNLMKGG | STKNWSGNSE | FHFYSINVGG | FFKLRAGEEI | SVQVSNPSLL |
318:
DPDQDATYFG | AFKVQDID
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Rat
Mouse
Human
ELISA Kit for Rat Tumor necrosis factor ligand superfamily member 11
ELISA Kit for Rat Tumor necrosis factor ligand superfamily member 11
ELISA Kit for Rat Tumor necrosis factor ligand superfamily member 11
CLIA Kit for Rat Tumor necrosis factor ligand superfamily member 11
CLIA Kit for Rat Tumor necrosis factor ligand superfamily member 11
CLIA Kit for Rat Tumor necrosis factor ligand superfamily member 11
Polyclonal Antibody for Rat Tumor necrosis factor ligand superfamily member 11
Polyclonal Antibody for Rat Tumor necrosis factor ligand superfamily member 11
Polyclonal Antibody for Rat Tumor necrosis factor ligand superfamily member 11
Monoclonal Antibody for Rat Tumor necrosis factor ligand superfamily member 11
Monoclonal Antibody for Rat Tumor necrosis factor ligand superfamily member 11
Monoclonal Antibody for Rat Tumor necrosis factor ligand superfamily member 11
Protein for Rat Tumor necrosis factor ligand superfamily member 11
Protein for Rat Tumor necrosis factor ligand superfamily member 11
Protein for Rat Tumor necrosis factor ligand superfamily member 11
R&D Technical Data
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Precision
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Recovery
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Linearity
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Citations
[1].
Victoria Clérigues, Maria Isabel Guillén, Miguel Angel Castejón, Francisco Gomard, Vicente Mirabete, Maria José Alcaraz
[2].
Y Che, C Bing, J Akhtar, et al.
[3].
HM Abuohashish, MM Ahmed, ss Al-RejAie, et al.
[4].
AP Tsakova, SK Surcheva, VS Bankova, et al.
References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
tissue :
Tibial bone .
2.
"Evidence that the rat osteopetrotic mutation toothless (tl) is not in the TNFSF11 (TRANCE, RANKL, ODF, OPGL) gene."
Odgren P.R.
,
Kim N.
,
van Wesenbeeck L.
,
MacKay C.
,
Mason-Savas A.
,
Safadi F.F.
,
Popoff S.N.
,
Lengner C.
,
van-Hul W.
,
Choi Y.
,
Marks S.C. Jr.
Int. J. Dev. Biol.45:853-859(2001)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] OF 266-318
strain :
Fischer 344 .